Biochemical Early Career Research Award
March 13, 2014
Toxicology Unit scientist Patricia Muller has been honoured with a prestigious Early Career Research Award from the Biochemical Society; the UK’s largest discipline based learned society in the biosciences. These awards recognize the impact of research carried out by early career scientists and their ability to demonstrate ambitions and aspirations consistent to achieving world-leading status.
Patricia is a Programme Leader Track scientist leading a group investigating the role of mutant p53 in invasion and chemo-resistance of cancer cells. p53 is a protein that is extremely important in protecting us against cancer. In some cancer cells p53 is lost, but in other cancer cells it is altered. When it becomes altered the cancer cells are more likely to spread through the body and also to become resistant to chemo-therapy. When Patricia started her career in cancer biology she discovered one of the mechanisms through which an altered p53 protein drives the spreading of the cancers cells through the body. Meanwhile she has discovered that similar mechanisms could underlie the chemo-resistance seen in mutant p53 cancers. Knowing these mechanims is important for the development of new drugs that prevent spreading and increase the sensitivity of cancer cells to current chemotherapy.
Patricia will present her award lecture at a Biochemical Society Conference in 2015.