Advanced Light Imaging
The Advanced Light Imaging Section provides a wide range of instruments and software for the acquisition, processing and analysis of light-captured images. The equipment is used by all Unit Research Groups together with external collaborators.
Within the Toxicology Unit, we have a range of instruments to capture images from a variety of experimental situations. The systems include three -scanning confocal microscopes, two of which are equipped with Mai Tai pulsing IR lasers for multi-photon imaging. Live cells can be imaged with an on-stage incubation system.
In addition, we have a new spinning-disk confocal incorporating a steerable UV ablation laser for DNA damage and other studies.
The Unit has a number of large wide-field microscope systems which are dedicated to time-lapse, calcium and live-cell imaging.
Support and user training is provided for all the instruments as well as help in analysing results using programs such as Volocity.
Haustein MD, Read DJ, Steinert JR, Pilati N, Dinsdale D, Forsythe ID.
J Physiol. 2010 Dec 1;588(Pt 23):4683-93. Epub 2010 Oct 11.
Tong H, Steinert JR, Robinson SW, Chernova T, Read DJ, Oliver DL, Forsythe ID.
J Physiol. 2010 May 1;588(Pt 9):1451-68. Epub 2010 Mar 8.