Dr. David Moore

Academic Clinical Lecturer

Headshot of David Moore

MRC Toxicology Unit
Hodgkin Building
PO Box 138
University of Leicester
Lancaster Road, Leicester

Email: dam18@leicester.ac.uk

Qualifications and Personal History

Dr. Moore previously trained as a medical Doctor as St. Bartholomew’s and the Royal London school of medicine, and is in the final stage of specialty training as a diagnostic pathologist.

BMedSci (Hons), University of London

MBBS, University of London

MD, University of Leicester

FRCPath, Royal College of Pathologists

Cert HAT, Royal College of Pathologists

Research Interests

  • Combined molecular and morphological characterisation of early lung adenocarcinoma.
  • Histological grading characteristics of lung adenocarcinoma with prognostic relevance.
  • Assessment of the use of next generation sequencing for use as a diagnostic tool in tumours of uncertain origin.
  • Identification of biomarkers of genomic instability, clinical implications and relevance to tumour biology and behaviour.

Selected Publications

    Moore DA, Saldanha GS, Ehdode A, Mughal MZ, Potter L, Dyall L, Pringle JH. Duplex
    ratio tests as diagnostic biomarkers in malignant melanoma. Journal Molecular Diagnostics. 2015

    Moore DA, Saldanha GS, Ehdode A, Potter L, Dyall L, Bury D, Pringle JH. Accurate detection of copy number changes in DNA extracted from formalin fixed paraffin embedded melanoma tissue using duplex ratio tests. Journal Molecular Diagnostics. 2013 Sep;15(5):687-94.

    Moore DA, Le Quesne JP. The molecular approach to diagnosis in lung cancer.
    Br J Hosp Med (Lond). 2015 May;76(5):C74-6

    Moore DA, Howard Pringle J, Saldanha GS. Prognostic Tissue Markers in Melanoma. Histopathology. 2012 Apr;60(5):679-89

    Rudraraju B, Droog M, Abdel-Fatah TM, Zwart W, Giannoudis A, Malki MI, Moore D, Patel H, Shaw J, Ellis IO, Chan S, Brooke GN, Nevedomskaya E, Nigro CL, Carroll J, Coombes RC, Bevan C, Ali S, Palmieri C. Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer. Breast Cancer Res Treat. 2014 Sep;147(2):295-309.

    Salem MK, Bown MJ, Sayers RD, West K, Moore D, Nicolaides A, Robinson TG, Naylor AR. Identification of Patients with a Histologically Unstable Carotid Plaque Using Ultrasonic Plaque Image Analysis. Eur J Vasc Endovasc Surg. 2014

    Salem MK, Sayers RD, Bown MJ, West K, Moore D, Robinson TG, Naylor AR. Features of Unstable Carotid Plaque During and After the Hyperacute Period Following TIA/Stroke. Eur J Vasc Endovasc Surg. 2013 Feb;45(2):114-20

    Salem MK, Vijaynagar B, Sayers RD, West K, Moore D, Robinson TG, Naylor AR, Bown MJ. Histologically Unstable Asymptomatic Carotid Plaques Have Altered Expression of Genes Involved in Chemokine Signalling Leading to Localised Plaque Inflammation and Rupture. Eur J Vasc Endovasc Surg. 2013 Feb;45(2):121-7

    Salem MK, Sayers RD, Bown MJ, West K, Moore D, Nicolaides A, Robinson TG, Naylor AR. Patients with Recurrent Ischaemic Events from Carotid Artery Disease have a Large Lipid Core and Low GSM. Eur J Vasc Endovasc Surg. 2012 Feb;43(2):147-53.

    Walton TJ, Avery C, Moore D, Mayer NJ, Rajesh A, Kockelbergh RC. Utility of renal mass biopsy in a UK tertiary referral centre. Br J Med & Surg Urol. British Journal of Medical and Surgical Urology 2012;5(5):216-23.

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