Dr. Joern Steinert

Programme Leader

Headshot of Dr Joern Steinert

MRC Toxicology Unit
Hodgkin Building
PO Box 138
University of Leicester
Lancaster Road, Leicester

Tel: +44 (0)116 252 5216
Email: js333@le.ac.uk

Qualifications and Personal History

2006-2013   MRC Investigator Scientist, MRC Toxicology Unit, Leicester

2004-2006   Postdoctoral Scientist, Interdisciplinary Center for Neurobiology, University of Heidelberg

2002-2004   Postdoctoral Scientist, Friedrich Miescher Laboratory (Max-Planck Institute), Tübingen

2001-2002   Postdoctoral Scientist, Centre for Cardiovascular Biology and Medicine, King’s College London

Selected Publications

    1. Robinson SW, Nugent ML, Dinsdale D and Steinert JR (2014). Prion protein facilitates synaptic vesicle release by enhancing release probability. Hum Mol Genet, Sep 1;23(17):4581-96
    2. Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Guerra-Martin M, Halliday M, Morgan J, Dinsdale D, Tsaytler P, Bertolotti A, Willis AE, Bushell M and Mallucci GR (2012). Sustained translational repression by eIF2α−P mediates prion neurodegeneration. Nature, 6;485(7399):507-11
    3. Steinert JR, Campesan S, Richards P, Kyriacou CP, Forsythe ID & Giorgini F (2012). Rab11 modulates synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington’s disease. Hum Mol Genet, Jul 1;21(13):2912-22
    4. Tozer AJB, Forsythe ID & Steinert JR (2012). Nitric oxide signalling augments neuronal voltage-gated L-type (CaV1) and P/Q-type (CaV2.1) in the mouse Medial Nucleus of the Trapezoid Body. PLOS One, 7(2):e32256. Epub 2012 Feb 28.
    5. Agostini M, Tucci P, Steinert JR, Candi E, Shalom-Feuerstein R, Rivetti di Val Cervo P, Sayan B, Forsythe ID, Rouleau M, Aberdam D, Knight RA, Nicotera P, McKeon F & Melino G (2011). miR-34a, induced by TAp73, regulates the expression of synaptic genes. PNAS 108, 21099-104.
    6. Steinert JR, Robinson SW, Tong H, Haustein MD, Kopp-Scheinpflug C & Forsythe ID (2011). Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitability. Neuron 71, 291-305.
    7. Steinert JR, Postlethwaite M, Jordan M, Chernova T & Forsythe ID (2010). Development and maturation of N-Methyl-D-Aspartate Receptors (NMDAR) and EPSCs at a glutamatergic synapse in the rat and mouse auditory brainstem in vitro. J Physiol 588, 447-463.
    8. Steinert JR, Chernova T & Forsythe ID (2010). Nitric Oxide in brain function, dysfunction and dementia. Neuroscientist 16, 435-452.
    9. Steinert JR, Wyatt AW, Jacob R & Mann GE (2009). Redox modulation of Ca2+ signaling in human endothelial and smooth muscle cells in pre-eclampsia. Antioxid Redox Signal 11, 1149-1163.
    10. Steinert JR, Kopp-Scheinpflug C, Baker C, Challiss RAJ, Mistry R, Haustein MD, Griffin SJ, Tong H, Graham BP & Forsythe ID (2008). Nitric oxide is a volume transmitter regulating neuronal excitability in the auditory pathway. Neuron 60, 642-656.
    11. Steinert JR, Kuromi H, Hellwig A, Knirr M, Wyatt AW, Kidokoro Y & Schuster CM (2006). Experience-dependent formation and recruitment of large vesicles from reserve pool. Neuron 50, 723-733. 

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