Dr. Lia Panman

Programme Leader

Headshot of Dr Lia Panman

MRC Toxicology Unit
Hodgkin Building
Lancaster Road

Tel: +44 (0)116 252 5552
Email: fwp20@mrc-tox.cam.ac.uk

Qualifications and Personal History

2012-Present: Programme Leader Track, MRC Toxicology Unit

2004-2012: Postdoctoral Researcher with Professor Thomas Perlmann, LICR, Stockholm, Sweden

1999-2004: PhD with Professor Rolf Zeller, University of Utrecht, The Netherlands

1993-1998: MSc Molecular Biology, University of Groningen, The Netherlands

Selected Publications

    Panman L*., Mong J*., Alekseenko Z., Kee N., StantonLW, EricsonJ. and Perlmann T. (2013). Transcription factor-induced lineage programming of noradrenaline and motor neurons from embryonic stem cells. Stem  Cells  in press (accepted version online 29/10/2013) * Joint first author

    Panman L., Perlmann T. (2011). Tracing lineages to uncover neuronal identity. BMC Biology 9, 51

    Deng Q., Andersson E., Hedlund E., Alekseenko Z., Panman L., Millonig J., Ericson J., Perlmann T.  (2011). Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development. Development 138, 3399-3408.

    Panman L., Andersson E., Hedlund E., Kee N., Mong J., Uhde C., Deng Q., Alekseenko Z., Sandberg R., Stanton L.W., Ericson J., Perlmann T. (2011). Transcription factor-induced lineage selection of stem cell derived neural progenitor cells. Cell Stem Cell 8(6), 663-675.

    Volakakis N., Kadkhodaei B., Joodmardi E., Wallis K., Panman L., Silvaggi J., Spiegelman B.M., Perlmann T. (2010). NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection. PNAS 107(27), 12317-22.

    Panman L., Galli A., Lagarde N., Michos O., Soete G., Zuniga A., Zeller R. (2006). Differential regulation of gene expression in the digit forming area of the mouse limb bud by SHH and gremlin 1/FGF-mediated epithelial-mesenchymal signalling. Development 133, 3419-28.

    Panman L*., Drenth T., teWelscher P., Zuniga A., Zeller R. (2005). Genetic interaction of Gli3 and Alx4 during limb development. Int. J. Dev. Biol. 49(4), 443-448. *Corresponding author

    Zuniga A., Michos O., Spitz F., Haramis., A. P. G., Panman L. Galli A., Vintersten K., Klasen C., Mansfield W., Kuc S., Dono R., Duboule D., Zeller R. (2004). Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes and Development 18, 1553-1564.

    Michos O., Panman L., Vintersten K., Beier K., Zeller R., Zuniga A. (2004). Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signalling controlling metanephric kidney and limb organogenesis.Development 131, 3401-3410.

    Panman L. and Zeller R. (2003). Patterning the limb before and after SHH signalling. J. Anatomy 202, 3-12.

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